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Research

Research, explained

Primary literature, summarized and cited.

Retatrutide phase 2: what the 2023 NEJM trial did and didn't show

A plain-language reading of the 48-week phase 2 obesity trial of an investigational triple-hormone receptor agonist.

Published 2026-10-11 · Last reviewed 2026-10-11 · Medical reviewer: pending assignment

How to read weight-loss trial numbers without being misled

Means, placebo adjustment, estimands, and why a trial average is not your personal forecast.

Published 2026-10-11 · Last reviewed 2026-10-11 · Medical reviewer: pending assignment